A former affiliate professor at Purdue College faked knowledge in two revealed papers and a whole bunch of photos in 16 grant purposes, in line with a U.S. authorities analysis watchdog.
Alice C. Chang, whose publications and grants listed her identify as Chun-Ju Chang, acquired almost $700,000 in funding from the Nationwide Institutes of Well being (NIH) by means of grant purposes that the U.S. Workplace of Analysis Integrity (ORI) mentioned contained faux knowledge. She will likely be banned from receiving federal grants for a decade – a extra extreme sanction than ORI has sometimes imposed in recent times.
In its findings, ORI mentioned Chang, who was an affiliate professor of primary medical sciences at Purdue’s Faculty of Veterinary Medication:
knowingly, deliberately, or recklessly falsified and/or fabricated knowledge from the identical mouse fashions or cell traces by reusing the information, with or with out manipulation, to characterize unrelated experiments from totally different mouse fashions or cell traces with totally different therapies in 300 eighty-four (384) determine panels in sixteen (16) grant purposes.
Two of the grant purposes had been funded. Chang acquired $688,196 from the Nationwide Most cancers Institute, a division of the (NIH), from 2018-2019 for “Concentrating on metformin-directed stem cell destiny in triple damaging breast most cancers.” The opposite grant ORI says was submitted in 2014 and funded, “Concentrating on cell polarity equipment to exhaust breast most cancers stem cell pool,” doesn’t present up in NIH RePorter. The remainder of the grants weren’t authorized.
We discovered a Chun-Ju Chang who’s dean of the Faculty of Life Sciences at China Medical College in Taiwan and has revealed papers with a bunch that Chun-Ju Chang at Purdue additionally revealed with. She didn’t instantly reply to our request for remark.
ORI’s discovering additionally said Chang faked knowledge in two papers supported by authorities funding by reusing figures reporting gene expression in mice and cells after drug therapies, relabeling them to say they confirmed the outcomes of various experiments. In accordance with the company, she has agreed to request corrections for the papers:
Between the 2 papers and 15 of the grant purposes, ORI mentioned that Chang reused gene expression knowledge, generally with manipulation, in 119 determine panels. She reused different sorts of knowledge and pictures in a whole bunch of figures throughout a number of grant purposes, ORI discovered.
In addition to correcting the 2 papers, Chang agreed to a 10-year ban from all federal contracting, together with grant funding. She additionally agreed to not serve in any advisory or consulting position with the U.S. Public Well being Service, which incorporates the NIH, for that point interval.